U.K. Scientists Publish Advanced Ambrotose Powder Serum N-glycosylation Study
A study published in the European Journal of Clinical Nutrition indicated that intake of Advanced Ambrotose® powder resulted in a significant shift towards increased sialylation in the N-glycosylation profile of the serum of healthy adults. To the authors’ knowledge, this is the first study which has shown that dietary changes can affect serum glycosylation profiles. The lead author was Dr. Azita Alavi, a Research Fellow at the Sir Joseph Hotung Centre for Musculoskeletal Disorders, Division of Cellular and Molecular Medicine, St. George’s University of London, U.K. Co–authors include St. George’s University researchers Professor John Axford, Dr Edward Tarelli and Dr Owen Fraser, and Professor Martin Bland, Department of Health Sciences, University of York, UK.
Alavi A, Fraser O, Tarelli E, Bland M, Axford J. (2011) An open-label dosing study to evaluate the safety and effects of a dietary plant-derived polysaccharide supplement on the N-glycosylation status of serum glycoproteins in healthy subjects. Eur J Clin Nutr, 1-9.
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